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https://hdl.handle.net/1959.11/21246
Title: | Emergence of a novel mutant PCV2b variant associated with clinical PCVAD in two vaccinated pig farms in the U.S. concurrently infected with PPV2 | Contributor(s): | Opriessnig, Tanja (author); Xiao, Chao-Ting (author); Gerber, Priscilla Freitas (author) ; Halbur, Patrick G (author) | Publication Date: | 2013 | DOI: | 10.1016/j.vetmic.2012.12.019 | Handle Link: | https://hdl.handle.net/1959.11/21246 | Abstract: | Porcine circovirus (PCV) type 2b (PCV2b) emerged in North America in 2005-2006. During May of 2012, PCVAD occurred in 10-18-week-old pigs in two farms within a production system that routinely vaccinated against PCV2. Both farms received replacement gilts from the same multiplier. A mutant PCV2b strain not previously present in North America was identified. The strain was found to be 99.9% identical to a recently described mutant PCV2 isolate reported in China in 2010 and thought to be more virulent than classical PCV2a or PCV2b strains. It is possible that the current PCV2a-based commercial vaccines are not fully protective against this new strain. In addition, emerging porcine parvovirus type 2 (PPV2) was detected in 55% of the serum samples (73/132), perhaps implying that PPV2 could be a cofactor in cases of PCVAD. | Publication Type: | Journal Article | Source of Publication: | Veterinary Microbiology, 163(1-2), p. 177-183 | Publisher: | Elsevier BV | Place of Publication: | Netherlands | ISSN: | 1873-2542 0378-1135 |
Fields of Research (FoR) 2008: | 070712 Veterinary Virology 070704 Veterinary Epidemiology 070703 Veterinary Diagnosis and Diagnostics |
Fields of Research (FoR) 2020: | 300914 Veterinary virology 300905 Veterinary epidemiology 300904 Veterinary diagnosis and diagnostics |
Socio-Economic Objective (SEO) 2008: | 830308 Pigs | Socio-Economic Objective (SEO) 2020: | 100410 Pigs | Peer Reviewed: | Yes | HERDC Category Description: | C1 Refereed Article in a Scholarly Journal |
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Appears in Collections: | Journal Article |
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