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Title: The relationship between childhood psychosocial stressor level and telomere length: a meta-analysis
Contributor(s): Hanssen, Louise (author); Schutte, Nicola  (author)orcid ; Malouff, John M  (author); Epel, Elissa S (author)
Publication Date: 2017
Open Access: Yes
DOI: 10.4081/hpr.2017.6378Open Access Link
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Abstract: This meta-analysis examined the association between the level of childhood psychosocial stressors and telomere length, an important health biomarker. The meta-analysis, including 27 samples and 16,238 participants, found a significant association of -0.08 between a higher level of childhood stressors and shorter telomere length at a mean age of 42 across studies. Moderator analyses showed a trend in the direction of effect sizes being significantly larger with shorter times between the stressors and telomere measurement. Moderator analyses showed significantly higher effect sizes for studies that used a categorical method for assessing child stressor level and for assays completed with qPCR rather than with the Southern blot method. There was no significant moderation of effect size by whether study assayed leukocytes or buccal cells, whether the study assessed child stressor level by memory-based recall versus archival records, and whether the study controlled for age, sex, or additional variables. The results, focused on childhood events, add to prior findings that perceived stress and negative emotions are associated with telomere length.
Publication Type: Journal Article
Source of Publication: Health Psychology Research, 5(1), p. 14-22
Publisher: Pagepress
Place of Publication: Italy
ISSN: 2420-8124
Fields of Research (FoR) 2008: 170106 Health, Clinical and Counselling Psychology
Fields of Research (FoR) 2020: 520302 Clinical psychology
Socio-Economic Objective (SEO) 2008: 929999 Health not elsewhere classified
Socio-Economic Objective (SEO) 2020: 200201 Determinants of health
Peer Reviewed: Yes
HERDC Category Description: C1 Refereed Article in a Scholarly Journal
Appears in Collections:Journal Article
School of Psychology

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