Ancient human genomes suggest three ancestral populations for present-day Europeans

2014

Lazaridis, Iosif

Patterson, Nick

Berger, Bonnie

Zemunik, Tatijana

Cooper, Alan

Capelli, Cristian

Thomas, Mark G

Ruiz-Linares, Andres

Tishkoff, Sarah A

Singh, Lalji

Thangaraj, Kumarasamy

Villems, Richard

Comas, David

Economou, Christos

Sukernik, Rem

Metspalu, Mait

Meyer, Matthias

Eichler, Evan E

Burger, Joachim

Slatkin, Montgomery

Paabo, Svante

Kelso, Janet

Reich, David

Krause, Johannes

Bollongino, Ruth

Fu, Qiaomei

Bos, Kirsten I

Nordenfelt, Susanne

Li, Heng

de Filippo, Cesare

Prufer, Kay

Sawyer, Susanna

Mittnik, Alissa

Posth, Cosimo

Haak, Wolfgang

Hallgren, Fredrik

Fornander, Elin

Rohland, Nadin

Delsate, Dominique

Francken, Michael

Guinet, Jean-Michel

Wahl, Joachim

Ayodo, George

Renaud, Gabriel

Babiker, Hamza A

Bailliet, Graciela

Balanovska, Elena

Balanovsky, Oleg

Barrantes, Ramiro

Bedoya, Gabriel

Ben-Ami, Haim

Bene, Judit

Berrada, Fouad

Bravi, Claudio M

Mallick, Swapan

Brisighelli, Francesca

Busby, George B J

Cali, Francesco

Churnosov, Mikhail

Cole, David E C

Corach, Daniel

Damba, Larissa

van Driem, George

Dryomov, Stanislav

Dugoujon, Jean-Michel

Kirsanow, Karola

Fedorova, Sardana A

Gallego Romero, Irene

Gubina, Marina

Hammer, Michael

Henn, Brenna M

Hervig, Tor

Hodoglugil, Ugur

Jha, Aashish R

Karachanak-Yankova, Sena

Khusainova, Rita

Sudmant, Peter H

Khusnutdinova, Elza

Kittles, Rick

Kivisild, Toomas

Klitz, William

Kucinskas, Vaidutis

Kushniarevich, Alena

Laredj, Leila

Litvinov, Sergey

Loukidis, Theologos

Mahley, Robert W

Schraiber, Joshua G

Melegh, Bela

Metspalu, Ene

Molina, Julio

Mountain, Joanna

Nakkalajarvi, Klemetti

Nesheva, Desislava

Nyambo, Thomas

Osipova, Ludmila

Parik, Juri

Platonov, Fedor

Castellano, Sergi

Posukh, Olga

Romano, Valentino

Rothhammer, Francisco

Rudan, Igor

Ruizbakiev, Ruslan

Sahakyan, Hovhannes

Sajantila, Antti

Salas, Antonio

Starikovskaya, Elena B

Tarekegn, Ayele

Lipson, Mark

Toncheva, Draga

Turdikulova, Shahlo

Uktveryte, Ingrida

Utevska, Olga

Vasquez, Rene

Villena, Mercedes

Voevoda, Mikhail

Winkler, Cheryl A

Yepiskoposyan, Levon

Zalloua, Pierre

Journal Article

en

Publication

Nature Publishing Group

United Kingdom

10.1038/nature13673

une:20892

We sequenced the genomes of a ~7,000-year-old farmer from Germany and eight ~8,000-year-old hunter-gatherers from Luxembourg and Sweden. We analysed these and other ancient genomes ¹⁻⁴ with 2,345 contemporary humans to show thatmost present-day Europeans derive from atleast three highly differentiated populations: west European hunter-gatherers, who contributed ancestry to all Europeans but not to Near Easterners; ancient north Eurasians related to Upper Palaeolithic Siberians³, who contributed to both Europeans and Near Easterners; and early European farmers, who were mainly of Near Eastern origin but also harboured west European hunter-gatherer related ancestry. We model these populations' deep relationships and show that early European farmers had 44% ancestry from a 'basal Eurasian' population that split before the diversification of other non-African lineages.

link

Nature, 513(7518), p. 409-413

1476-4687

0028-0836

409

413