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https://hdl.handle.net/1959.11/20059
Title: | The Effect of Exercise Training Intensity on Quality of Life in Heart Failure Patients: A Systematic Review and Meta-Analysis | Contributor(s): | Ostman, Cecilia (author); Jewiss, Daniel (author); Smart, Neil (author) | Publication Date: | 2017 | DOI: | 10.1159/000448088 | Handle Link: | https://hdl.handle.net/1959.11/20059 | Abstract: | Objectives: To establish if exercise training intensity produces different effect sizes for quality of life in heart failure. Background: Exercise intensity is the primary stimulus for physical and mental adaptation. Methods: We conducted a MEDLINE search (1985 to February 2016) for exercise-based rehabilitation trials in heart failure using the search terms 'exercise training', 'left ventricular dysfunction', 'peak Vo₂', 'cardiomyopathy', and 'systolic heart dysfunction'. Results: Twenty-five studies were included; 4 (16%) comprised high-, 10 (40%) vigorous-, 9 (36%) moderate- and 0 (0%) low-intensity groups; two studies were unclassified. The 25 studies provided a total of 2,385 participants, 1,223 exercising and 1,162 controls (36,056 patient-hours of training). Analyses reported significant improvement in total Minnesota living with heart failure (MLWHF) total score [mean difference (MD) -8.24, 95% CI -11.55 to -4.92, p < 0.00001]. Physical MLWHF score was significantly improved in all studies ( MD -2.89, 95% CI -4.27 to -1.50, p < 0.00001). MLWHF total score was significantly reduced after high- (MD -13.74, 95% CI -21.34 to -6.14, p = 0.0004) and vigorous-intensity training (MD -8.56, 95% CI -12.77 to -4.35, p < 0.0001) but not moderate-intensity training. A significant improvement in the total MLWHF score was seen after aerobic training (MD -3.87, 95% CI -6.97 to -0.78, p = 0.01), and combined aerobic and resistance training (MD -9.82, 95% CI -15.71 to -3.92, p = 0.001), but not resistance training. Conclusions: As exercise training intensity rises, so may the magnitude of improvement in quality of life in exercising patients. Aerobic-only or combined aerobic and resistance training may offer the greatest improvements in quality of life. | Publication Type: | Journal Article | Source of Publication: | Cardiology, 136(2), p. 79-89 | Publisher: | S Karger AG | Place of Publication: | Switzerland | ISSN: | 1421-9751 0008-6312 |
Fields of Research (FoR) 2008: | 110602 Exercise Physiology 110201 Cardiology (incl. Cardiovascular Diseases) |
Fields of Research (FoR) 2020: | 420702 Exercise physiology 320101 Cardiology (incl. cardiovascular diseases) |
Socio-Economic Objective (SEO) 2008: | 920103 Cardiovascular System and Diseases | Socio-Economic Objective (SEO) 2020: | 200101 Diagnosis of human diseases and conditions | Peer Reviewed: | Yes | HERDC Category Description: | C1 Refereed Article in a Scholarly Journal |
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Appears in Collections: | Journal Article School of Science and Technology |
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