Selection of SNP Panels for Parentage Testing

Title
Selection of SNP Panels for Parentage Testing
Publication Date
2014
Author(s)
Gondro, C
( author )
OrcID: https://orcid.org/0000-0003-0666-656X
Email: cgondro2@une.edu.au
UNE Id une-id:cgondro2
Strucken, E M
( author )
OrcID: https://orcid.org/0000-0002-2715-0733
Email: estrucke@une.edu.au
UNE Id une-id:estrucke
Lee, H K
Song, K D
Lee, S H
Type of document
Conference Publication
Language
en
Entity Type
Publication
Publisher
American Society of Animal Science
Place of publication
Champaign, United States of America
UNE publication id
une:20058
Abstract
Correct parentage assignment is a fundamental requirement for a successful breeding program so that production performances can be linked back to the correct families to improve estimates of breeding values. In this study, we evaluated the influence of SNP panel sizes for parentage testing in two species (cattle and sheep) with very different genetic structures. Results suggest that small parentage panels will not port well across breeds and should be designed specifically for a particular breed. If cross breed panels are needed around 450 SNP should be used. Finally, we developed an evolutionary algorithm based on differential evolution to optimize selection of SNP marker panels for parentage assignment. Results show that the algorithm is more efficient at selecting markers for the panel than rule based marker selection.
Link
Citation
Proceedings of the 10th World Congress on Genetics Applied to Livestock Production (WCGALP) (Methods and Tools: Bioinformatics), p. 1-3
Start page
1
End page
3

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