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Title: Disorder-specific versus transdiagnostic and clinician-guided versus self-guided treatment for major depressive disorder and comorbid anxiety disorders: A randomized controlled trial
Contributor(s): Titov, N (author); Dear, BF (author); McEvoy, PM (author); Staples, LG (author); Terides, MD (author); Karin, E (author); Sheehan, J (author); Johnston, L (author); Gandy, M (author); Fogliati, VJ (author); Wootton, Bethany (author)
Publication Date: 2015
Open Access: Yes
DOI: 10.1016/j.janxdis.2015.08.002Open Access Link
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Abstract: Disorder-specific cognitive behavior therapy (DS-CBT) is effective at treating major depressive disorder (MDD) while transdiagnostic CBT (TD-CBT) addresses both principal and comorbid disorders by targeting underlying and common symptoms. The relative benefits of these two models of therapy have not been determined. Participants with MDD (n = 290) were randomly allocated to receive an internet delivered TD-CBT or DS-CBT intervention delivered in either clinician-guided (CG-CBT) or self-guided (SG-CBT) formats. Large reductions in symptoms of MDD (Cohen's d ≥ 1.44; avg. reduction ≥ 45%) and moderate-to-large reductions in symptoms of comorbid generalised anxiety disorder (Cohen's d ≥ 1.08; avg. reduction ≥ 43%), social anxiety disorder (Cohen's d ≥ 0.65; avg. reduction ≥ 29%) and panic disorder (Cohen's d ≥ 0.45; avg. reduction ≥ 31%) were found. No marked or consistent differences were observed across the four conditions, highlighting the efficacy of different forms of CBT at treating MDD and comorbid disorders.
Publication Type: Journal Article
Source of Publication: Journal of Anxiety Disorders, v.35, p. 88-102
Publisher: Pegamon Press
Place of Publication: United Kingdom
ISSN: 0887-6185
Field of Research (FOR): 170106 Health, Clinical and Counselling Psychology
Socio-Economic Outcome Codes: 920410 Mental Health
Peer Reviewed: Yes
HERDC Category Description: C1 Refereed Article in a Scholarly Journal
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