Scope and limitations of a DMF bio-alternative within Sonogashira cross-coupling and Cacchi-type annulation

Title
Scope and limitations of a DMF bio-alternative within Sonogashira cross-coupling and Cacchi-type annulation
Publication Date
2016
Author(s)
Wilson, Kirsty L
Kennedy, Alan R
Murray, Jane
Greatrex, Ben
( author )
OrcID: https://orcid.org/0000-0002-0356-4966
Email: bgreatre@une.edu.au
UNE Id une-id:bgreatre
Jamieson, Craig
Watson, Allan J B
Type of document
Journal Article
Language
en
Entity Type
Publication
Publisher
Beilstein - Institut zur Foerderung der Chemischen Wissenschaften
Place of publication
Germany
DOI
10.3762/bjoc.12.187
UNE publication id
une:19765
Abstract
Pd-catalysed C-C bond formation is an essential tool within the pharmaceutical and agrochemical industries. Many of these reactions rely heavily on polar aprotic solvents; however, despite their utility, these solvents are incompatible with the drive towards more sustainable chemical synthesis. Herein, we describe the scope and limitations of an alternative to DMF derived from renewable sources (CyreneTM) in Sonogashira cross-coupling and Cacchi-type annulations.
Link
Citation
Beilstein Journal of Organic Chemistry, v.12, p. 2005-2011
ISSN
1860-5397
Start page
2005
End page
2011

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