Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/19575
Title: Scope and limitations of a DMF bio-alternative within Sonogashira cross-coupling and Cacchi-type annulation
Contributor(s): Wilson, Kirsty L (author); Kennedy, Alan R (author); Murray, Jane (author); Greatrex, Ben  (author)orcid ; Jamieson, Craig (author); Watson, Allan J B (author)
Publication Date: 2016
Open Access: Yes
DOI: 10.3762/bjoc.12.187Open Access Link
Handle Link: https://hdl.handle.net/1959.11/19575
Abstract: Pd-catalysed C-C bond formation is an essential tool within the pharmaceutical and agrochemical industries. Many of these reactions rely heavily on polar aprotic solvents; however, despite their utility, these solvents are incompatible with the drive towards more sustainable chemical synthesis. Herein, we describe the scope and limitations of an alternative to DMF derived from renewable sources (CyreneTM) in Sonogashira cross-coupling and Cacchi-type annulations.
Publication Type: Journal Article
Source of Publication: Beilstein Journal of Organic Chemistry, v.12, p. 2005-2011
Publisher: Beilstein - Institut zur Foerderung der Chemischen Wissenschaften
Place of Publication: Frankfurt am Main, Germany
ISSN: 1860-5397
Field of Research (FOR): 030504 Organic Green Chemistry
030503 Organic Chemical Synthesis
030399 Macromolecular and Materials Chemistry not elsewhere classified
Socio-Economic Outcome Codes: 970103 Expanding Knowledge in the Chemical Sciences
970106 Expanding Knowledge in the Biological Sciences
Peer Reviewed: Yes
HERDC Category Description: C1 Refereed Article in a Scholarly Journal
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