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https://hdl.handle.net/1959.11/19575| Title: | Scope and limitations of a DMF bio-alternative within Sonogashira cross-coupling and Cacchi-type annulation | Contributor(s): | Wilson, Kirsty L (author); Kennedy, Alan R (author); Murray, Jane (author); Greatrex, Ben (author) ; Jamieson, Craig (author); Watson, Allan J B (author) |
Publication Date: | 2016 | Open Access: | Yes | DOI: | 10.3762/bjoc.12.187 |
Handle Link: | https://hdl.handle.net/1959.11/19575 | Abstract: | Pd-catalysed C-C bond formation is an essential tool within the pharmaceutical and agrochemical industries. Many of these reactions rely heavily on polar aprotic solvents; however, despite their utility, these solvents are incompatible with the drive towards more sustainable chemical synthesis. Herein, we describe the scope and limitations of an alternative to DMF derived from renewable sources (CyreneTM) in Sonogashira cross-coupling and Cacchi-type annulations. | Publication Type: | Journal Article | Source of Publication: | Beilstein Journal of Organic Chemistry, v.12, p. 2005-2011 | Publisher: | Beilstein - Institut zur Foerderung der Chemischen Wissenschaften | Place of Publication: | Frankfurt am Main, Germany | ISSN: | 1860-5397 | Field of Research (FOR): | 030504 Organic Green Chemistry 030503 Organic Chemical Synthesis 030399 Macromolecular and Materials Chemistry not elsewhere classified |
Socio-Economic Objective (SEO): | 970103 Expanding Knowledge in the Chemical Sciences 970106 Expanding Knowledge in the Biological Sciences |
Peer Reviewed: | Yes | HERDC Category Description: | C1 Refereed Article in a Scholarly Journal | Statistics to Oct 2018: | Visitors: 63 |
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| Appears in Collections: | Journal Article |
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