Please use this identifier to cite or link to this item:
https://hdl.handle.net/1959.11/19574
Title: | The Iridoid Myodesert-1-ene and Elemol/Eudesmol are found in Distinct Chemotypes of the Australian Aboriginal Medicinal Plant 'Eremophila dalyana' (Scrophulariaceae) | Contributor(s): | Sadgrove, Nicholas (author); Collins, Timothy (author); Legendre, Sarah (author); Klepp, Julian (author); Jones, Graham L (author)![]() ![]() |
Publication Date: | 2016 | Handle Link: | https://hdl.handle.net/1959.11/19574 | Abstract: | The strongly aromatic Australian desert species 'Eremophila dalyana' is an Aboriginal medicinal plant that continues to be used today in Central Australia in the treatment of respiratory complaints and 'Sarcoptes scabiei' infestation. Using hydrodistillation of aerial parts of the plant, the new natural product myodesert-1- ene was isolated in two disjunct populations at up to 98% of the volatiles present in the hydrodistilled oils. Weak antimicrobial activities were observed for whole oils and myodesert-1-ene. Activities in the hydrodistilled oil were attributed to the antimicrobial sesquiterpenes elemol and eudesmol which showed good activity when isolated and were relatively abundant in the chemotype used medicinally. The biogenesis of myodesert-1-ene from iridodial is proposed. | Publication Type: | Journal Article | Source of Publication: | Natural Product Communications, 11(9), p. 1211-1214 | Publisher: | Natural Product Inc | Place of Publication: | United States of America | ISSN: | 1555-9475 1934-578X |
Fields of Research (FoR) 2008: | 030503 Organic Chemical Synthesis 030401 Biologically Active Molecules 030502 Natural Products Chemistry |
Fields of Research (FoR) 2020: | 340401 Biologically active molecules 349999 Other chemical sciences not elsewhere classified 340503 Organic chemical synthesis |
Socio-Economic Objective (SEO) 2008: | 970103 Expanding Knowledge in the Chemical Sciences 970106 Expanding Knowledge in the Biological Sciences |
Socio-Economic Objective (SEO) 2020: | 280105 Expanding knowledge in the chemical sciences 280102 Expanding knowledge in the biological sciences |
Peer Reviewed: | Yes | HERDC Category Description: | C1 Refereed Article in a Scholarly Journal | Publisher/associated links: | http://www.naturalproduct.us/ |
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Appears in Collections: | Journal Article |
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