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|Title:||Pleiotropic Multi-Trait Genome-Wide Association Reveals Putative Candidate Genes for Fatty Acid Composition in Australian Sheep||Contributor(s):||Bolormaa, Sunduimijid (author); Van Der Werf, Julius H (author) ; Hayes, B J (author); Goddard, M E (author); Daetwyler, Hans D (author)||Publication Date:||2015||Open Access:||Yes||Handle Link:||https://hdl.handle.net/1959.11/19476||Open Access Link:||http://www.aaabg.org/aaabghome/AAABG21papers/Bolormaa21049.pdf||Abstract:||The aims of this paper were to detect SNP and genes that affect the fatty acid composition and other carcass and meat quality traits in sheep. We performed genome-wide association studies (OW AS) for 56 traits including carcass weights, muscling, fatness, tenderness, meat color, mineral content, and fatty acid composition on 10,613 animals genotyped for 510,174 SNPs. The use of ameta-analysis to combine information from the 56 traits increased the power to detect QTL compared with the single trait analyses. We found pleiotropic QTL, which appear to cluster into 5 functional groups based on their trait effects. Candidate genes were identified in the groups that have functions consistent with the biology of the traits.||Publication Type:||Conference Publication||Conference Name:||21st Conference of the Association for the Advancement of Animal Breeding and Genetics, Lorne, Australia, 28th - 30th September, 2015||Conference Details:||21st Conference of the Association for the Advancement of Animal Breeding and Genetics, Lorne, Australia, 28th - 30th September, 2015||Source of Publication:||Proceedings of the Twenty-first Conference of the Association for the Advancement of Animal Breeding and Genetics, p. 49-52||Publisher:||AAABG: Association for the Advancement of Animal Breeding and Genetics||Place of Publication:||Bundoora, Australia||Field of Research (FOR):||070201 Animal Breeding||Peer Reviewed:||Yes||HERDC Category Description:||E1 Refereed Scholarly Conference Publication||Other Links:||http://www.aaabg.org/aaabghome/proceedings21.php||Series Name:||Proceedings of the AAABG ... Conference||Series Number :||21||Statistics to Oct 2018:||Visitors: 92
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