Early Onset Severe Disease and Premature Mortality in Indigenous Australians with Non-Cystic Fibrosis Bronchiectasis

Abstract

Aim: To describe the natural history of adult non-cystic fibrosis bronchiectasis (non-CF BEx) and identify risk factors associated with premature mortality within a cohort of Indigenous and non-Indigenous Australians. Methods: A retrospective cohort study of Indigenous and non-Indigenous Australians with non-CF bronchiectasis from January 1 2009 until January 15 2014. Five-year survival was determined and multivariate Cox proportional hazard modelling used to identify independent predictors of mortality. Results: 85 Indigenous (all Aboriginal Australian) and 79 non-Indigenous Australian adults were included. ...