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Title: Clinically Meaningful Blood Pressure Reductions With Low Intensity Isometric Handgrip Exercise: A Randomized Trial
Contributor(s): Hess, Nicole  (author); Carlson, Debra (author); Inder, Jodie (author); Jesulola, Emmanuel (author); McFarlane, James R (author)orcid ; Smart, Neil  (author)orcid 
Publication Date: 2016
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Abstract: There exists no examination of what is the minimum antihypertensive threshold intensity for isometric exercise training. Twenty two normotensive participants were randomly assigned to training intensities at either 5% or 10% of their maximal contraction. Twenty participants completed the study. Clinical meaningful, but not statistically significant, reductions in systolic blood pressure were observed in both 5% and 10% groups -4.04 mm Hg (95 % CI -8.67 to +0.59, p=0.08) and -5.62 mm Hg (95 % CI -11.5 to +0.29, p=0.06) respectively after 6 weeks training. No diastolic blood pressure reductions were observed in either 5 % -0.97 mm Hg (95 % CI -2.56 to +0.62, p=0.20) or 10 % MVC +1.8 mm Hg (95 % CI -1.29 to +4.89, p=0.22) groups respectively after training. In those unable to complete isometric exercise at the traditional 30 % intensity, our results suggest there is no difference between 5 and 10 % groups and based on the principle of regression to the mean, this could mean both interventions induce a similar placebo-effect.
Publication Type: Journal Article
Source of Publication: Physiological Research, 65(3), p. 461-468
Publisher: Akademie Ved Ceske Republiky
Place of Publication: Czech Republic
ISSN: 1802-9973
Field of Research (FOR): 110201 Cardiology (incl. Cardiovascular Diseases)
Socio-Economic Outcome Codes: 920103 Cardiovascular System and Diseases
Peer Reviewed: Yes
HERDC Category Description: C1 Refereed Article in a Scholarly Journal
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