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Title: Bioavailability and efficacy of orally administered flunixin, carprofen and ketoprofen in a pain model in sheep
Contributor(s): Marini, Danila (author); Pippia, Joe (author); Colditz, Ian (author); Hinch, Geoffrey (author)orcid ; Petherick, Carol (author); Lee, Caroline (author)
Publication Date: 2014
Open Access: Yes
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Abstract: The pain from routine husbandry practices performed on sheep can last several days and sheep often don't receive therapeutic interventions to provide pain relief. Attractive candidates for long-acting pain relief are non-steroidal anti-inflammatory drugs (NSAIDs). If NSAIDs can be shown to alleviate pain and inflammation when administered orally in sheep, they could be incorporated in feed, providing producers with a practical method to provide long-term pain relief in sheep. The aim of this research was to test the bioavailability and efficacy of carprofen, ketoprofen and flunixin administered orally using a lameness model (turpentine (0.1 ml) injected into one forelimb) developed to enable objective quantitative assessment of the analgesic, antipyretic and anti-inflammatory actions of NSAIDs in sheep.
Publication Type: Conference Publication
Conference Name: ISAE 2014: 48th Congress of the International Society for Applied Ethology, Vitoria-Gasteiz, Spain, 29th July - 2nd August, 2014
Source of Publication: Moving on: Proceedings of the 48th Congress of the International Society for Applied Ethology (ISAE 2014), p. 220-220
Publisher: Wageningen Academic Publishers
Place of Publication: Wageningen, The Netherlands
Field of Research (FOR): 070202 Animal Growth and Development
HERDC Category Description: E3 Extract of Scholarly Conference Publication
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