Bioavailability and efficacy of orally administered flunixin, carprofen and ketoprofen in a pain model in sheep

Author(s)
Marini, Danila
Pippia, Joe
Colditz, Ian
Hinch, Geoffrey
Petherick, Carol
Lee, Caroline
Publication Date
2014
Abstract
The pain from routine husbandry practices performed on sheep can last several days and sheep often don't receive therapeutic interventions to provide pain relief. Attractive candidates for long-acting pain relief are non-steroidal anti-inflammatory drugs (NSAIDs). If NSAIDs can be shown to alleviate pain and inflammation when administered orally in sheep, they could be incorporated in feed, providing producers with a practical method to provide long-term pain relief in sheep. The aim of this research was to test the bioavailability and efficacy of carprofen, ketoprofen and flunixin administered orally using a lameness model (turpentine (0.1 ml) injected into one forelimb) developed to enable objective quantitative assessment of the analgesic, antipyretic and anti-inflammatory actions of NSAIDs in sheep.
Citation
Moving on: Proceedings of the 48th Congress of the International Society for Applied Ethology (ISAE 2014), p. 220-220
ISBN
9789086867974
9789086862450
Link
Language
en
Publisher
Wageningen Academic Publishers
Title
Bioavailability and efficacy of orally administered flunixin, carprofen and ketoprofen in a pain model in sheep
Type of document
Conference Publication
Entity Type
Publication

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