Please use this identifier to cite or link to this item:
https://hdl.handle.net/1959.11/18355
Title: | Clinical application of low-dose phase contrast breast CT: methods for the optimization of the reconstruction workflow | Contributor(s): | Pacile, S (author); Brun, F (author); Accardo, A (author); Tromba, G (author); Gureyev, Timur (author) ; Dullin, C (author); Nesterets, Yakov (author); Dreossi, D (author); Mohammadi, S (author); Tonutti, M (author); Stacul, F (author); Lockie, D (author); Zanconati, F (author) | Publication Date: | 2015 | Open Access: | Yes | DOI: | 10.1364/boe.6.003099 | Handle Link: | https://hdl.handle.net/1959.11/18355 | Abstract: | Results are presented of a feasibility study of three-dimensional X-ray tomographic mammography utilising in-line phase contrast. Experiments were performed at SYRMEP beamline of Elettra synchrotron. A specially designed plastic phantom and a mastectomy sample containing a malignant lesion were used to study the reconstructed image quality as a function of different image processing operations. Detailed evaluation and optimization of image reconstruction workflows have been carried out using combinations of several advanced computed tomography algorithms with different pre-processing and post-processing steps. Special attention was paid to the effect of phase retrieval on the diagnostic value of the reconstructed images. A number of objective image quality indices have been applied for quantitative evaluation of the results, and these were compared with subjective assessments of the same images by three experienced radiologists and one pathologist. The outcomes of this study provide practical guidelines for the optimization of image processing workflows in synchrotron-based phase-contrast mammo-tomography. | Publication Type: | Journal Article | Source of Publication: | Biomedical Optics Express, 6(8), p. 3099-3112 | Publisher: | Optical Society of America | Place of Publication: | United States of America | ISSN: | 2156-7085 | Fields of Research (FoR) 2008: | 020501 Classical and Physical Optics 029903 Medical Physics |
Fields of Research (FoR) 2020: | 510302 Classical and physical optics 510502 Medical physics |
Socio-Economic Objective (SEO) 2008: | 920203 Diagnostic Methods | Socio-Economic Objective (SEO) 2020: | 200399 Provision of health and support services not elsewhere classified 200101 Diagnosis of human diseases and conditions |
Peer Reviewed: | Yes | HERDC Category Description: | C1 Refereed Article in a Scholarly Journal |
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Appears in Collections: | Journal Article |
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