Nesterets, Yakov

Gureyev, Timur

Tromba, Giuliana

Mayo, Sheridan C

Stevenson, Andrew W

Thompson, Darren

Brown, Jeremy M C

Kitchen, Marcus J

Pavlov, Konstantin M

Lockie, Darren

Brun, Francesco

2015

Results are presented of a recent experiment at the Imaging and Medical beamline of the Australian Synchrotron intended to contribute to the implementation of low-dose high-sensitivity three-dimensional mammographic phase-contrast imaging, initially at synchrotrons and subsequently in hospitals and medical imaging clinics. The effect of such imaging parameters as X-ray energy, source size, detector resolution, sample-to-detector distance, scanning and data processing strategies in the case of propagation-based phase-contrast computed tomography (CT) have been tested, quantified, evaluated and optimized using a plastic phantom simulating relevant breast-tissue characteristics. Analysis of the data collected using a Hamamatsu CMOS Flat Panel Sensor, with a pixel size of 100 mm, revealed the presence of propagation-based phase contrast and demonstrated significant improvement of the quality of phase-contrast CT imaging compared with conventional (absorption-based) CT, at medically acceptable radiation doses.

Journal of Synchrotron Radiation, 22(6), p. 1509-1523

1600-5775

0909-0495

https://hdl.handle.net/1959.11/18114

Wiley-Blackwell Publishing Ltd

A feasibility study of X-ray phase-contrast mammographic tomography at the Imaging and Medical beamline of the Australian Synchrotron

Journal Article

Publication