Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/16459
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dc.contributor.authorPanwar, Shalinien
dc.contributor.authorMcFarlane, James Ren
dc.date.accessioned2015-01-13T11:48:00Z
dc.date.issued2006en
dc.identifier.citationSociety for Reproductive Biology Thirty-Seventh Annual Scientific Meeting Program and Abstracts, p. 81-81en
dc.identifier.urihttps://hdl.handle.net/1959.11/16459en
dc.description.abstractLeptin, a 16kDa polypeptide, has long been known to have a role in reproduction as exogenous leptin administration can reverse the sterility of ob/ob mice which lack functional leptin. Leptin binds to cell surface receptors (Ob-R) and signals via STAT/JAK signal transduction pathway. This ligand receptor system is mandatory for embryonic implantation in rodents as withdrawl of leptin infusion in ob/ob females shortly after fertilization impairs implantation. Leptin and its receptors are expressed in human and mouse endometrium. Leptin has been immunolocalized in human and mouse preimplantation embryos and promotes mouse preimplantation embryo development through Ob-R signaling. The aim of our experiment was to study the impact of blocking leptin signaling in the mouse endometrium by giving intrauterine injections of leptin antiserum on day 1 and day 3 of pregnancy.en
dc.languageenen
dc.publisherSociety for Reproductive Biologyen
dc.relation.ispartofSociety for Reproductive Biology Thirty-Seventh Annual Scientific Meeting Program and Abstractsen
dc.titleLeptin is critical for successful implantation in miceen
dc.typeConference Publicationen
dc.relation.conference37th Annual Scientific Meeting of the Society for Reproductive Biology, Gold Coast, Australia, 20th - 23rd August, 2006en
dc.subject.keywordsAnimal Physiology - Systemsen
local.contributor.firstnameShalinien
local.contributor.firstnameJames Ren
local.subject.for2008060603 Animal Physiology - Systemsen
local.subject.seo2008970111 Expanding Knowledge in the Medical and Health Sciencesen
local.profile.schoolHuman Biology and Physiologyen
local.profile.emailjmcfarla@une.edu.auen
local.output.categoryE3en
local.record.placeauen
local.record.institutionUniversity of New Englanden
local.identifier.epublicationsrecordune-20100422-123215en
local.publisher.placeonlineen
local.identifier.runningnumberAbstract 280en
local.format.startpage81en
local.format.endpage81en
local.contributor.lastnamePanwaren
local.contributor.lastnameMcFarlaneen
dc.identifier.staffune-id:spanwaren
dc.identifier.staffune-id:jmcfarlaen
local.profile.orcid0000-0003-4429-5384en
local.profile.roleauthoren
local.profile.roleauthoren
local.identifier.unepublicationidune:16696en
dc.identifier.academiclevelAcademicen
local.title.maintitleLeptin is critical for successful implantation in miceen
local.output.categorydescriptionE3 Extract of Scholarly Conference Publicationen
local.relation.urlhttp://www.srb.org.au/assets/SRBSociety/PastProceedings/SRB2006.pdfen
local.conference.details37th Annual Scientific Meeting of the Society for Reproductive Biology, Gold Coast, Australia, 20th - 23rd August, 2006en
local.description.statisticsepubsVisitors: 96<br />Views: 127<br />Downloads: 0en
local.search.authorPanwar, Shalinien
local.search.authorMcFarlane, James Ren
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