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https://hdl.handle.net/1959.11/16459
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Tanwar, P S | en |
dc.contributor.author | McFarlane, J R | en |
dc.date.accessioned | 2015-01-13T11:48:00Z | - |
dc.date.issued | 2006 | - |
dc.identifier.citation | Society for Reproductive Biology Thirty-Seventh Annual Scientific Meeting Program and Abstracts, p. 81-81 | en |
dc.identifier.uri | https://hdl.handle.net/1959.11/16459 | - |
dc.description.abstract | Leptin, a 16kDa polypeptide, has long been known to have a role in reproduction as exogenous leptin administration can reverse the sterility of ob/ob mice which lack functional leptin. Leptin binds to cell surface receptors (Ob-R) and signals via STAT/JAK signal transduction pathway. This ligand receptor system is mandatory for embryonic implantation in rodents as withdrawl of leptin infusion in ob/ob females shortly after fertilization impairs implantation. Leptin and its receptors are expressed in human and mouse endometrium. Leptin has been immunolocalized in human and mouse preimplantation embryos and promotes mouse preimplantation embryo development through Ob-R signaling. The aim of our experiment was to study the impact of blocking leptin signaling in the mouse endometrium by giving intrauterine injections of leptin antiserum on day 1 and day 3 of pregnancy. | en |
dc.language | en | en |
dc.publisher | Society for Reproductive Biology | en |
dc.relation.ispartof | Society for Reproductive Biology Thirty-Seventh Annual Scientific Meeting Program and Abstracts | en |
dc.title | Leptin is critical for successful implantation in mice | en |
dc.type | Conference Publication | en |
dc.relation.conference | SRB 2006: 37th Annual Conference of the Society for Reproductive Biology | en |
dc.subject.keywords | Animal Physiology - Systems | en |
local.contributor.firstname | P S | en |
local.contributor.firstname | J R | en |
local.subject.for2008 | 060603 Animal Physiology - Systems | en |
local.subject.seo2008 | 970111 Expanding Knowledge in the Medical and Health Sciences | en |
local.profile.school | School of Science and Technology | en |
local.profile.email | jmcfarla@une.edu.au | en |
local.output.category | E3 | en |
local.record.place | au | en |
local.record.institution | University of New England | en |
local.identifier.epublicationsrecord | une-20100422-123215 | en |
local.date.conference | 20th - 23rd August, 2006 | en |
local.conference.place | Gold Coast, Australia | en |
local.publisher.place | online | en |
local.identifier.runningnumber | Abstract 280 | en |
local.format.startpage | 81 | en |
local.format.endpage | 81 | en |
local.contributor.lastname | Tanwar | en |
local.contributor.lastname | McFarlane | en |
dc.identifier.staff | une-id:spanwar | en |
dc.identifier.staff | une-id:jmcfarla | en |
local.profile.orcid | 0000-0003-4429-5384 | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.identifier.unepublicationid | une:16696 | en |
dc.identifier.academiclevel | Academic | en |
local.title.maintitle | Leptin is critical for successful implantation in mice | en |
local.output.categorydescription | E3 Extract of Scholarly Conference Publication | en |
local.relation.url | http://www.srb.org.au/assets/SRBSociety/PastProceedings/SRB2006.pdf | en |
local.conference.details | SRB 2006: 37th Annual Conference of the Society for Reproductive Biology, Gold Coast, Australia, 20th - 23rd August, 2006 | en |
local.search.author | Tanwar, P S | en |
local.search.author | McFarlane, J R | en |
local.uneassociation | Unknown | en |
local.year.published | 2006 | en |
local.date.start | 2006-08-20 | - |
local.date.end | 2006-08-23 | - |
Appears in Collections: | Conference Publication |
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