Please use this identifier to cite or link to this item:
https://hdl.handle.net/1959.11/1508
Title: | Stereoselective synthesis, natural occurrence and CB₂ receptor binding affinities of alkylamides from herbal medicines such as 'Echinacea' sp. | Contributor(s): | Matovic, N (author); Matthias, A (author); Gertsch, J (author); Raduner, S (author); Bone, Kerry (author); Lehmann, RP (author); DeVoss, JJ (author) | Publication Date: | 2007 | DOI: | 10.1039/b615487e | Handle Link: | https://hdl.handle.net/1959.11/1508 | Abstract: | A divergent synthesis of (2E,4E,8E,10E)- and (2E,4E,8E,10Z)-N-isobutyldodeca-2,4,8,10-tetraenamides from pent-4-yn-1-ol allowed identification of the (2E,4E,8E,10Z)-isomer for the first time in Echinacea species. A short, stereoselective synthesis of the (2E,4E,8E,10Z)-isomer is also described which allowed further biological evaluation of this material, and the demonstration that this isomer does not occur in 'Spilanthes mauritiana' as previously reported. | Publication Type: | Journal Article | Source of Publication: | Organic & Biomolecular Chemistry, 5(1), p. 169-174 | Publisher: | Royal Society of Chemistry | Place of Publication: | United Kingdom | ISSN: | 1477-0539 1477-0520 |
Fields of Research (FoR) 2008: | 060199 Biochemistry and Cell Biology not elsewhere classified | Peer Reviewed: | Yes | HERDC Category Description: | C1 Refereed Article in a Scholarly Journal |
---|---|
Appears in Collections: | Journal Article |
Files in This Item:
File | Description | Size | Format |
---|
SCOPUSTM
Citations
31
checked on Mar 23, 2024
Page view(s)
1,012
checked on Mar 24, 2024
Items in Research UNE are protected by copyright, with all rights reserved, unless otherwise indicated.