Please use this identifier to cite or link to this item:
https://hdl.handle.net/1959.11/14939
Title: | Consuming a small-moderate dose of red wine alone can alter the glucose-insulin relationship | Contributor(s): | Kokavec, Anna (author) ; Halloran, Mark A (author) | Publication Date: | 2010 | DOI: | 10.1139/Y10-092 | Handle Link: | https://hdl.handle.net/1959.11/14939 | Abstract: | The aim in the present study was to assess the effect of small-moderate red wine ingestion on the level of serum insulin and plasma glucose when nutritional status is varied. Twenty nondiabetic males (19-22 years) participated in the study. In the fasting trial, all participants underwent a 6 h fast prior to consuming 4 standard units of red wine (40 g alcohol) or the equivalent amount of placebo as dealcoholized wine (containing <0.5% alcohol, 0% resveratrol) over a 135 min period. Alternatively, in the feeding trial, participants consumed food for 45 min prior to ingesting 4 standard units of red wine (40 g alcohol) or placebo over 135 min. Serum insulin and plasma glucose were assessed at regular 45 min intervals during all trials. The results showed a significant decrease in the level of serum insulin and no significant change in plasma glucose concentration in the fasting trial. Alternatively, a significant alcohol-induced decrease in plasma glucose and no change in serum insulin occurred when red wine alone was consumed after food. It was concluded that red wine can alter the glucose-insulin relationship and ingesting red wine alone (without food) should not be encouraged in nondiabetic individuals. | Publication Type: | Journal Article | Source of Publication: | Canadian Journal of Physiology and Pharmacology, 88(12), p. 1147-1156 | Publisher: | NRC Research Press | Place of Publication: | Canada | ISSN: | 1205-7541 0008-4212 |
Fields of Research (FoR) 2008: | 119999 Medical and Health Sciences not elsewhere classified 111603 Systems Physiology 111502 Clinical Pharmacology and Therapeutics |
Socio-Economic Objective (SEO) 2008: | 920104 Diabetes 920414 Substance Abuse 920401 Behaviour and Health |
Peer Reviewed: | Yes | HERDC Category Description: | C1 Refereed Article in a Scholarly Journal |
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Appears in Collections: | Journal Article |
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