Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/14477
Title: Comparisons of Identical by State and Identical by Descent Relationship Matrices Derived from SNP Markers in Genomic Evaluation
Contributor(s): Clark, Sam A  (author)orcid ; Kinghorn, Brian  (author); Van Der Werf, Julius H  (author)orcid 
Publication Date: 2013
Open Access: Yes
Handle Link: https://hdl.handle.net/1959.11/14477
Open Access Link: http://www.aaabg.org/aaabghome/AAABG20papers/clark20261.pdfOpen Access Link
Abstract: In animal populations, family members inherit alleles through common ancestors and these shared regions are referred to as identical by descent (IBD). Furthermore, animals may also share alleles due to a random association with no known common inheritance pattern. This identity by state (IBS) also covers known relationships, such that regions that are IBD are also IBS, however regions that are IBS may not always be IBD. In the genetic evaluation of livestock, IBD and IBS information can be used to build the genomic relationship matrix (GRM) and breeding values can be predicted using genomic best linear unbiased prediction (gBLUP). This study compares a number of different methods to construct the GRM, using IBD and IBS information. Each method was evaluated using a reference dataset of 1781 Merino sheep and validated using 164 progeny tested sires that had accurate breeding values. Estimates of variance components were also compared. There was no significant difference between the accuracy achieved by the IBS and IBD methods. However the accuracy of the EBVs decreased as a greater restriction was applied to whether a region was IBD or not IBD. Furthermore, estimates of variance components were substantially different for IBD and IBS methods.
Publication Type: Conference Publication
Conference Name: 20th Conference of the Association for the Advancement of Animal Breeding and Genetics: Translating Science into Action, Napier, New Zealand, 20th - 23rd October, 2013
Conference Details: 20th Conference of the Association for the Advancement of Animal Breeding and Genetics: Translating Science into Action, Napier, New Zealand, 20th - 23rd October, 2013
Source of Publication: Proceedings of the Twentieth Conference of the Association for the Advancement of Animal Breeding and Genetics, p. 261-265
Publisher: AAABG: Association for the Advancement of Animal Breeding and Genetics
Place of Publication: Palmerston North, New Zealand
Field of Research (FOR): 060412 Quantitative Genetics (incl Disease and Trait Mapping Genetics)
Socio-Economic Outcome Codes: 830311 Sheep - Wool
Peer Reviewed: Yes
HERDC Category Description: E1 Refereed Scholarly Conference Publication
Series Name: Proceedings of the AAABG ... Conference
Series Number : 20
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