Inherited knee disorders in the Medici family

Author(s)
Lippi, Donatella
Matucci-Cerinic, Marco
Albury, William Randall
Weisz, George M
Publication Date
2014
Abstract
Reconstructing a medical condition which was existent centuries ago is limited by the lack of contemporaneous evidence-based descriptions in the accounts given by physicians and other observers. Despite these limitations modern paleopathological evidence, supplemented by techniques of historical investigation, have led to the conclusion that males in the Medici family typically suffered from a complex clinical entity with a triple pathology of stenotic spinal ankylosis, recurrent peripheral joint disease and erythematous skin disease; the Medici Syndrome. Examination of the knee joint is illustrative of recurrent joint disease both in the primary and secondary lines of the family. Pictorial and sculptural representations, if used cautiously, can assist in this retrospective process. The six cases presented here illustrate the involvement of the knee joint where the joint destruction ultimately led to an ankylosis.
Citation
The Knee, 21(1), p. 2-5
ISSN
1873-5800
0968-0160
Link
Language
en
Publisher
Elsevier BV
Title
Inherited knee disorders in the Medici family
Type of document
Journal Article
Entity Type
Publication

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