Please use this identifier to cite or link to this item:
|Title:||Characterisation of Two Australian Isolates of Marek's Disease Virus 'in Vivo' Including Neuropathotyping||Contributor(s):||Al-Kadher, Salih Jabir Wajid (author); Walkden-Brown, Steve W (author) ; Islam, Afm Fakhrul (author); Renz, Katrin (author)||Publication Date:||2013||Handle Link:||https://hdl.handle.net/1959.11/14030||Abstract:||Virulent Marek's disease virus (MDV) induces early (1-3 weeks after challenge) neurological signs in chickens free of maternal antibody directed against MDV. A system for neuropathotyping MDV on the basis of the timing and severity of these signs has been reported in the USA and we report its application as part of the evaluation of virulence of Australian MDV isolates MPF23 and MPF57 at 3 different challenge doses in specific pathogen free (SPF) chicks over a 56-day post challenge period. MPF23 was the more pathogenic of the two viruses as assessed by a range of measures including mortality rate (81% versus 62%) and incidence of gross Marek's disease (MD) lesions (95% versus 76%). This was reflected in a clearly different pattern of clinical illness over the 56-day period with the MPF23 group showing earlier, more sustained and more severe clinical signs in the period 26-56 day post challenge (dpc). However there were few differences during the 0-23 dpc period used for the USA neuropathotyping system. The observed pattern during this period classifies both viruses as neuropathotype B consistent with a vv pathotype under the pathotying classification of the Avian Diseases and Oncology Laboratory (ADOL) of the USDA.||Publication Type:||Conference Publication||Conference Name:||24th Annual Australian Poultry Science Symposium, Sydney, Australia, 17th - 20th February, 2013||Conference Details:||24th Annual Australian Poultry Science Symposium, Sydney, Australia, 17th - 20th February, 2013||Source of Publication:||Proceedings of the 24th Annual Australian Poultry Science Symposium, p. 230-233||Publisher:||Poultry Research Foundation, University of Sydney||Place of Publication:||Sydney, Australia||ISSN:||1034-6260||Field of Research (FOR):||070712 Veterinary Virology||Peer Reviewed:||Yes||HERDC Category Description:||E1 Refereed Scholarly Conference Publication||Other Links:||http://sydney.edu.au/vetscience/apss/proceed.shtml||Series Name:||Australian Poultry Science Symposium Proceedings||Series Number :||24||Statistics to Oct 2018:||Visitors: 369
|Appears in Collections:||Conference Publication|
Files in This Item:
checked on May 3, 2019
Items in Research UNE are protected by copyright, with all rights reserved, unless otherwise indicated.