Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/13931
Title: A Binary Classifier Using SNP Data for Prediction of Phenotypic Outcomes in Hanwoo (Korean) Cattle
Contributor(s): Detterer, Dion (author); Lee, Seung Hwan (author); Kwan, Paul H  (author); Gondro, Cedric  (author)orcid 
Publication Date: 2013
Handle Link: https://hdl.handle.net/1959.11/13931
Abstract: Korean 'Hanwoo' cattle are prized for their high marbling ability and meat quality. Classically, these cattle possess a homogeneous yellow coat colouring, with farmers believing that 'Hanwoo' with white spotted coats are crossbred and therefore unacceptable for breeding purposes. In this study we first attempted to determine if the coat spots were due to a non-'Hanwoo' genetic background or, alternatively, if the trait is intrinsic to the breed. By genotyping 232 (136 spotted) animals from half-sib families on the Illumina Bovine 50K SNP array, we compared the genotyped Hanwoo to other unrelated 'Hanwoo' and European taurine breeds using principal component analysis. Results showed no evidence of crossbreeding in the spotted animals. A differential evolution algorithm was then used to evolve a classifier for the trait which selected 12 SNP with an accuracy of ~82% in separating individuals; further investigation using only haplotypes inherited from the sires resulted in a marked improvement to ~92% accuracy for these 12 SNP. This research highlights the potential for using these SNP as genetic markers to either entirely remove the trait from the population in the long term or manage matings so that the trait is not expressed in the offspring.
Publication Type: Conference Publication
Conference Name: 20th Conference of the Association for the Advancement of Animal Breeding and Genetics: Translating Science into Action, Napier, New Zealand, 20th - 23rd October, 2013
Conference Details: 20th Conference of the Association for the Advancement of Animal Breeding and Genetics: Translating Science into Action, Napier, New Zealand, 20th - 23rd October, 2013
Grant Details: ARC/DP130100542
Source of Publication: Proceedings of the Twentieth Conference of the Association for the Advancement of Animal Breeding and Genetics, p. 511-514
Publisher: AAABG: Association for the Advancement of Animal Breeding and Genetics
Place of Publication: Palmerston North, New Zealand
Field of Research (FOR): 080108 Neural, Evolutionary and Fuzzy Computation
070201 Animal Breeding
060405 Gene Expression (incl Microarray and other genome-wide approaches)
Peer Reviewed: Yes
HERDC Category Description: E1 Refereed Scholarly Conference Publication
Other Links: http://www.aaabg.org/aaabghome/proceedings20.php
Series Name: Proceedings of the AAABG ... Conference
Series Number : 20
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Appears in Collections:Conference Publication

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