Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/13930
Title: A Study on Effects of Family and Haplotype Blocks on Conservation of Gene Expression Traits in Half Sib Sheep Families
Contributor(s): Al-Mamun, Hawlader A (author); Kwan, Paul H  (author); Tellam, Ross L (author); Kijas, James W (author); Gondro, Cedric  (author)orcid 
Publication Date: 2013
Handle Link: https://hdl.handle.net/1959.11/13930
Abstract: The objective of this study was to explore the relationship between SNP and haplotype variation on gene expression traits. The data used included expression levels from 24,128 probe sets of 'logissimus lumborum' muscle from 38 half-sib Poll Dorset sheep from six families and genotypes from 49,034 SNPs collected from the same animals. The analytical approaches used sought to analyse the effects of family and haplotype blocks on conservation of gene expression traits in this sheep population. Our study indicated that there is a genetic component in gene expression traits and hence gene expression is heritable to non-negligible extent. On average, our estimated heritability for gene expression obtained from skeletal muscle samples of sheep is 0.27 and 0.29 based on two different approaches. These preliminary results are consistent with previous heritability estimates.
Publication Type: Conference Publication
Conference Name: 20th Conference of the Association for the Advancement of Animal Breeding and Genetics: Translating Science into Action, Napier, New Zealand, 20th - 23rd October, 2013
Conference Details: 20th Conference of the Association for the Advancement of Animal Breeding and Genetics: Translating Science into Action, Napier, New Zealand, 20th - 23rd October, 2013
Grant Details: ARC/DP130100542
Source of Publication: Proceedings of the Twentieth Conference of the Association for the Advancement of Animal Breeding and Genetics, p. 266-269
Publisher: AAABG: Association for the Advancement of Animal Breeding and Genetics
Place of Publication: Palmerston North, New Zealand
Field of Research (FOR): 080105 Expert Systems
060405 Gene Expression (incl Microarray and other genome-wide approaches)
070201 Animal Breeding
Peer Reviewed: Yes
HERDC Category Description: E1 Refereed Scholarly Conference Publication
Other Links: http://www.aaabg.org/aaabghome/proceedings20.php
Series Name: Proceedings of the AAABG ... Conference
Series Number : 20
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