Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/13930
Title: A Study on Effects of Family and Haplotype Blocks on Conservation of Gene Expression Traits in Half Sib Sheep Families
Contributor(s): Al-Mamun, Hawlader A (author); Kwan, Paul H  (author); Tellam, Ross L (author); Kijas, James W (author); Gondro, Cedric  (author)orcid 
Publication Date: 2013
Handle Link: https://hdl.handle.net/1959.11/13930
Abstract: The objective of this study was to explore the relationship between SNP and haplotype variation on gene expression traits. The data used included expression levels from 24,128 probe sets of 'logissimus lumborum' muscle from 38 half-sib Poll Dorset sheep from six families and genotypes from 49,034 SNPs collected from the same animals. The analytical approaches used sought to analyse the effects of family and haplotype blocks on conservation of gene expression traits in this sheep population. Our study indicated that there is a genetic component in gene expression traits and hence gene expression is heritable to non-negligible extent. On average, our estimated heritability for gene expression obtained from skeletal muscle samples of sheep is 0.27 and 0.29 based on two different approaches. These preliminary results are consistent with previous heritability estimates.
Publication Type: Conference Publication
Conference Details: AAABG 2013: 20th Conference of the Association for the Advancement of Animal Breeding and Genetics: Translating Science into Action, Napier, New Zealand, 20th - 23rd October, 2013
Grant Details: ARC/DP130100542
Source of Publication: Proceedings of the Association for the Advancement of Animal Breeding and Genetics, v.20, p. 266-269
Publisher: Association for the Advancement of Animal Breeding and Genetics (AAABG)
Place of Publication: Armidale, Australia
ISSN: 1328-3227
Fields of Research (FoR) 2008: 080105 Expert Systems
060405 Gene Expression (incl Microarray and other genome-wide approaches)
070201 Animal Breeding
Fields of Research (FoR) 2020: 460206 Knowledge representation and reasoning
310505 Gene expression (incl. microarray and other genome-wide approaches)
300109 Non-genetically modified uses of biotechnology
Socio-Economic Objective (SEO) 2008: 970107 Expanding Knowledge in the Agricultural and Veterinary Sciences
830310 Sheep - Meat
970108 Expanding Knowledge in the Information and Computing Sciences
Socio-Economic Objective (SEO) 2020: 280101 Expanding knowledge in the agricultural, food and veterinary sciences
100412 Sheep for meat
280115 Expanding knowledge in the information and computing sciences
Peer Reviewed: Yes
HERDC Category Description: E1 Refereed Scholarly Conference Publication
Publisher/associated links: http://www.aaabg.org/aaabghome/proceedings20.php
Appears in Collections:Conference Publication

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