Generic substitution in the treatment of epilepsy: Patient attitudes and perceptions

Title
Generic substitution in the treatment of epilepsy: Patient attitudes and perceptions
Publication Date
2013
Author(s)
Ngo, Suong N T
Stupans, Ieva
McKinnon, Ross A
Type of document
Journal Article
Language
en
Entity Type
Publication
Publisher
Academic Press
Place of publication
United States of America
DOI
10.1016/j.yebeh.2012.10.032
UNE publication id
une:14132
Abstract
There have been considerable debates about bioequivalence and generic substitution of certain critical care drugs. We aimed to understand patient attitudes and perceptions about generic substitution in the treatment of epilepsy. In this pilot study, a self-administered anonymous survey was completed by 47 patients with epilepsy. The response rate by postal mail was 6.7%. More than 70% of the patients were concerned about the effectiveness of generic antiepileptic drugs, and 68% of the patients were not comfortable receiving generics to treat their epilepsy. About 87% of the patients thought that their antiepileptic drug should only be substituted with a generic with their consent, and 64% of the patients believed that substitution should only take place with the consent of their doctor. Considerable concern exists among patients about generic substitution in the treatment of epilepsy. More data regarding whether generic antiepileptic drugs are bioequivalent in clinical situations would help to address patient concerns.
Link
Citation
Epilepsy & Behavior, 26(1), p. 64-66
ISSN
1525-5050
1525-5069
Start page
64
End page
66

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