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Title: Generic substitution in the treatment of epilepsy: Patient attitudes and perceptions
Contributor(s): Ngo, Suong N T (author); Stupans, Ieva  (author); McKinnon, Ross A (author)
Publication Date: 2013
DOI: 10.1016/j.yebeh.2012.10.032
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Abstract: There have been considerable debates about bioequivalence and generic substitution of certain critical care drugs. We aimed to understand patient attitudes and perceptions about generic substitution in the treatment of epilepsy. In this pilot study, a self-administered anonymous survey was completed by 47 patients with epilepsy. The response rate by postal mail was 6.7%. More than 70% of the patients were concerned about the effectiveness of generic antiepileptic drugs, and 68% of the patients were not comfortable receiving generics to treat their epilepsy. About 87% of the patients thought that their antiepileptic drug should only be substituted with a generic with their consent, and 64% of the patients believed that substitution should only take place with the consent of their doctor. Considerable concern exists among patients about generic substitution in the treatment of epilepsy. More data regarding whether generic antiepileptic drugs are bioequivalent in clinical situations would help to address patient concerns.
Publication Type: Journal Article
Source of Publication: Epilepsy & Behavior, 26(1), p. 64-66
Publisher: Academic Press
Place of Publication: United States of America
ISSN: 1525-5050
Field of Research (FOR): 111503 Clinical Pharmacy and Pharmacy Practice
Socio-Economic Objective (SEO): 920111 Nervous System and Disorders
Peer Reviewed: Yes
HERDC Category Description: C1 Refereed Article in a Scholarly Journal
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Appears in Collections:Journal Article
School of Science and Technology

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