Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/13566
Title: Chemical and Biological Characterization of Novel Essential Oils from 'Eremophila bignoniiflora' (F. Muell) (Myoporaceae): A Traditional Aboriginal Australian Bush Medicine
Contributor(s): Sadgrove, Nicholas (author); Hitchcock, Maria (author); Watson, Kenneth (author); Jones, Graham L (author)orcid 
Publication Date: 2013
DOI: 10.1002/ptr.4889
Handle Link: https://hdl.handle.net/1959.11/13566
Abstract: Essential oils were extracted by hydrodistillation from the traditional Australian medicinal plant 'Eremophila bignoniiflora', characterized chemically and then screened for bioactivity. Characterization and quantification were completed using gas chromatography-mass spectrometry (GC-MS) and GC-flame ionization detection, respectively. Antimicrobial capacity was assessed using disc diffusion and micro-titre plate broth dilution and further characterized using thin layer chromatography followed by bioautography to assign activity to separated individual active components. Antifungal capacity was investigated using micro-titre plate broth dilution against pathogenic Trichophyton species. Free radical scavenging ability was assessed using the diphenylpicrylhydradyl reaction in methanol. The predominant components of the essential oil were fenchyl-acetate and bornyl-acetate. However, bioautography indicated antimicrobial ability to be largely linked to the less abundant, more polar constituents. Oils displayed only modest antifungal ability against pathogenic Trichophyton species associated with dermatophytosis, but moderate to high antimicrobial activity, particularly against the yeast Candida albicans and the bacteria 'Staphylococcus epidermidis'. Essential oils exhibited relatively low free radical scavenging ability. Speculation over the role of essential oils in the traditional medicinal applications of 'E. bignoniiflora' follows, exploring correlations between traditional use and investigated bioactivities.
Publication Type: Journal Article
Source of Publication: Phytotherapy Research, 27(10), p. 1508-1516
Publisher: John Wiley & Sons Ltd
Place of Publication: United Kingdom
ISSN: 1099-1573
0951-418X
Field of Research (FOR): 060799 Plant Biology not elsewhere classified
110403 Traditional Aboriginal and Torres Strait Islander Medicine and Treatments
111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
Peer Reviewed: Yes
HERDC Category Description: C1 Refereed Article in a Scholarly Journal
Statistics to Oct 2018: Visitors: 681
Views: 783
Downloads: 0
Appears in Collections:Journal Article

Files in This Item:
2 files
File Description SizeFormat 
Show full item record

SCOPUSTM   
Citations

8
checked on Nov 30, 2018

Page view(s)

90
checked on Mar 2, 2019
Google Media

Google ScholarTM

Check

Altmetric

SCOPUSTM   
Citations

 

WEB OF SCIENCETM
Citations

 

Items in Research UNE are protected by copyright, with all rights reserved, unless otherwise indicated.