Differences in neurobiological pathways of four "clinical content" subtypes of depression

Title
Differences in neurobiological pathways of four "clinical content" subtypes of depression
Publication Date
2013
Author(s)
Sharpley, Christopher
( author )
OrcID: https://orcid.org/0000-0001-7922-4848
Email: csharpl3@une.edu.au
UNE Id une-id:csharpl3
Bitsika, Vicki
Type of document
Journal Article
Language
en
Entity Type
Publication
Publisher
Elsevier BV
Place of publication
Netherlands
DOI
10.1016/j.bbr.2013.08.030
UNE publication id
une:13772
Abstract
Although often considered as a mental disorder, depression is best described as a behavioral neurobiological phenomenon. In addition, although usually reported as a unitary diagnosis, major depressive episode is composed of a range of different symptoms that can occur in nearly 1500 possible combinations to fulfill the required diagnostic criterion. To investigate and describe the underlying behavioral and neurobiological substrates of these symptoms, they were clustered into "clinical content" subtypes of depression according to their predominant common behavioral characteristics. These subtypes were then found to possess different neurobiological pathways that argue for different treatment approaches.
Link
Citation
Behavioural Brain Research, v.256, p. 368-376
ISSN
1872-7549
0166-4328
Start page
368
End page
376

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