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Title: Do prostate cancer patients suffer more from depressed mood or anhedonia?
Contributor(s): Sharpley, Christopher  (author)orcid ; Bitsika, Vicki  (author); Christie, David R H  (author)
Publication Date: 2013
DOI: 10.1002/pon.3203
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Abstract: Objective: This study aimed to compare the prevalence of depressed mood and anhedonia in a sample of men with prostate cancer (PCa) and to determine which of these key symptoms contributed most to the overall depressive status of that sample. Method: From Zung Self-rating Depression Scale (SDS) responses collected on 526 PCa patients, direct comparisons were made between the prevalence of the first two DSM-IV-TR symptoms of Major Depressive Episode. These symptoms were then tested for their predictive power on depression total score and Zung's criteria for 'clinically significant' depression. Results: Mean scores for anhedonia were significantly higher than for depressed mood, and nearly 25 times as many patients had a high score for anhedonia as for depressed mood. The same pattern of results was apparent for those patients who had clinically significant levels of depression. Anhedonia was a more powerful predictor of total SDS depression score for the entire sample as well as for those patients with more severe depression. Conclusion: Because the biological basis for anhedonia is different to that for depressed mood, treatment options also differ for patients who show a preponderance of anhedonia in their depressive symptomatology. Suggestions are made for treatment choices for these PCa patients.
Publication Type: Journal Article
Source of Publication: Psycho-Oncology, 22(8), p. 1718-1723
Publisher: John Wiley & Sons Ltd
Place of Publication: United Kingdom
ISSN: 1099-1611
Field of Research (FOR): 110319 Psychiatry (incl Psychotherapy)
Socio-Economic Outcome Codes: 920410 Mental Health
Peer Reviewed: Yes
HERDC Category Description: C1 Refereed Article in a Scholarly Journal
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