Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/12755
Title: Nutrition-Gene Interactions (Post-Genomics): Changes in gene expression through nutritional manipulations
Contributor(s): Harper, Gregory S (author); Lehnert, Sigrid A (author); Greenwood, Paul (author)
Publication Date: 2005
DOI: 10.1007/1-4020-3312-5_31
Handle Link: https://hdl.handle.net/1959.11/12755
Abstract: This paper discusses the effects of severe nutritional restriction, both pre- and post-weaning, on development of skeletal muscle in food animals. Given recent predictions about growth in demand for muscle-foods in developing countries, the global community will need to face the food-feed dilemma, and balance efficiency of production against the quality-of-life aspects of local livestock husbandry. It is likely that production animals will be grown in successively more marginal environments and at higher stocking rates on unimproved pastures. Understanding the nutritional limits to animal growth at the level of muscle gene networks will help us find optima for nutrition, growth rate and meat yield. Genomic approaches give us unprecedented capacity to map the networks of control under nutritionally restricted conditions, though the challenges remain of identifying steps that regulate substrate flux. The paper describes some approaches currently being taken to understanding muscle development, and concludes that the genes contributing to two ruminant phenotypes should be mapped and characterized. These are: the capacity to depress metabolic rate in response to nutritional restriction; and the capacity to exhibit compensatory growth after restriction is relieved.
Publication Type: Book Chapter
Source of Publication: Applications of Gene-Based Technologies for Improving Animal Production and Health in Developing Countries, p. 411-428
Publisher: Springer
Place of Publication: Dordrecht, Netherlands
ISBN: 9781402033117
9781402033124
Fields of Research (FoR) 2008: 070202 Animal Growth and Development
070702 Veterinary Anatomy and Physiology
070204 Animal Nutrition
Socio-Economic Objective (SEO) 2008: 830399 Livestock Raising not elsewhere classified
HERDC Category Description: B1 Chapter in a Scholarly Book
Publisher/associated links: http://trove.nla.gov.au/work/20956138
Editor: Editor(s): Harinder PS Makkar and Gerrit J Viljoen
Appears in Collections:Book Chapter

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