Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/12519
Full metadata record
DC FieldValueLanguage
dc.contributor.authorClark, Sam Aen
dc.contributor.authorHickey, Jen
dc.contributor.authorDaetwyler, H Den
dc.contributor.authorVan Der Werf, Julius Hen
dc.date.accessioned2013-05-10T16:42:00Z-
dc.date.issued2012-
dc.identifier.citationGenetics Selection Evolution, v.44, p. 1-9en
dc.identifier.issn1297-9686en
dc.identifier.issn0999-193Xen
dc.identifier.urihttps://hdl.handle.net/1959.11/12519-
dc.description.abstractBackground: The theory of genomic selection is based on the prediction of the effects of genetic markers in linkage disequilibrium with quantitative trait loci. However, genomic selection also relies on relationships between individuals to accurately predict genetic value. This study aimed to examine the importance of information on relatives versus that of unrelated or more distantly related individuals on the estimation of genomic breeding values. Methods: Simulated and real data were used to examine the effects of various degrees of relationship on the accuracy of genomic selection. Genomic Best Linear Unbiased Prediction (gBLUP) was compared to two pedigree based BLUP methods, one with a shallow one generation pedigree and the other with a deep ten generation pedigree. The accuracy of estimated breeding values for different groups of selection candidates that had varying degrees of relationships to a reference data set of 1750 animals was investigated. Results: The gBLUP method predicted breeding values more accurately than BLUP. The most accurate breeding values were estimated using gBLUP for closely related animals. Similarly, the pedigree based BLUP methods were also accurate for closely related animals, however when the pedigree based BLUP methods were used to predict unrelated animals, the accuracy was close to zero. In contrast, gBLUP breeding values, for animals that had no pedigree relationship with animals in the reference data set, allowed substantial accuracy.en
dc.languageenen
dc.publisherBioMed Central Ltden
dc.relation.ispartofGenetics Selection Evolutionen
dc.titleThe importance of information on relatives for the prediction of genomic breeding values and the implications for the makeup of reference data sets in livestock breeding schemesen
dc.typeJournal Articleen
dc.identifier.doi10.1186/1297-9686-44-4en
dcterms.accessRightsGolden
dc.subject.keywordsQuantitative Genetics (incl Disease and Trait Mapping Genetics)en
local.contributor.firstnameSam Aen
local.contributor.firstnameJen
local.contributor.firstnameH Den
local.contributor.firstnameJulius Hen
local.subject.for2008060412 Quantitative Genetics (incl Disease and Trait Mapping Genetics)en
local.subject.seo2008830301 Beef Cattleen
local.subject.seo2008830302 Dairy Cattleen
local.profile.schoolSchool of Environmental and Rural Scienceen
local.profile.schoolEnvironmental and Rural Scienceen
local.profile.schoolEnvironmental and Rural Scienceen
local.profile.schoolSchool of Environmental and Rural Scienceen
local.profile.emailsclark37@une.edu.auen
local.profile.emailjvanderw@une.edu.auen
local.output.categoryC1en
local.record.placeauen
local.record.institutionUniversity of New Englanden
local.identifier.epublicationsrecordune-20130408-143448en
local.publisher.placeUnited Kingdomen
local.identifier.runningnumber4en
local.format.startpage1en
local.format.endpage9en
local.identifier.scopusid84863581942en
local.peerreviewedYesen
local.identifier.volume44en
local.access.fulltextYesen
local.contributor.lastnameClarken
local.contributor.lastnameHickeyen
local.contributor.lastnameDaetwyleren
local.contributor.lastnameVan Der Werfen
dc.identifier.staffune-id:sclark37en
dc.identifier.staffune-id:jhickey5en
dc.identifier.staffune-id:jvanderwen
local.profile.orcid0000-0001-8605-1738en
local.profile.orcid0000-0003-2512-1696en
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.identifier.unepublicationidune:12726en
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
local.title.maintitleThe importance of information on relatives for the prediction of genomic breeding values and the implications for the makeup of reference data sets in livestock breeding schemesen
local.output.categorydescriptionC1 Refereed Article in a Scholarly Journalen
local.search.authorClark, Sam Aen
local.search.authorHickey, Jen
local.search.authorDaetwyler, H Den
local.search.authorVan Der Werf, Julius Hen
local.uneassociationUnknownen
local.identifier.wosid000302059000001en
local.year.published2012en
local.subject.for2020310506 Gene mappingen
local.subject.seo2020100401 Beef cattleen
local.subject.seo2020100402 Dairy cattleen
Appears in Collections:Journal Article
Files in This Item:
2 files
File Description SizeFormat 
Show simple item record

SCOPUSTM   
Citations

232
checked on Mar 2, 2024

Page view(s)

1,090
checked on Mar 7, 2023

Download(s)

2
checked on Mar 7, 2023
Google Media

Google ScholarTM

Check

Altmetric


Items in Research UNE are protected by copyright, with all rights reserved, unless otherwise indicated.