Dietary Supplements of Vitamins and Antioxidants Modulate Oxidative Stress in Baby Boomers

Abstract

Numerous epidemiological studies have shown a strong correlation between antioxidant-rich diets and a reduction in the risk of cardiovascular disease and cancer. Although a number of randomized large scale intervention trials have shown a small to moderate effects of supplements, others have shown equivocal or even negative effects. It is clear that the physiological effects and efficacy of dietary intake of antioxidant and vitamin supplements in humans remains controversial. In this study on individuals aged 35 to 60 years (baby boomers) we investigated the nature and extent of protection offered by a commercially available antioxidant mixture at the recommended dosage, to various biochemical parameters associated with oxidative and free radical stress.