Please use this identifier to cite or link to this item:
https://hdl.handle.net/1959.11/10600
Title: | Effect of fasting and dexamethasone on binding characteristics of canine erythrocyte insulin receptors | Contributor(s): | Dieberg, Gudrun (author) ; Sartin, JL (author); Kemppainen, RJ (author); Oliver, EH (author) | Publication Date: | 1986 | Handle Link: | https://hdl.handle.net/1959.11/10600 | Abstract: | Insulin binding characteristics of canine erythrocyte insulin receptors were studied before and after a 72-hour fast, and one and three days following glucocorticoid (dexamethasone) administration. The 72-hour fast tended to increase maximum insulin binding, but no significant differences were found. The administration of dexamethasone resulted in an increased maximum binding of insulin to its receptors which, at day 1, was due to an increase in receptor concentration, and at day 3, to an increased insulin binding affinity of the receptor. These data suggest that the erythrocyte insulin receptor may be useful in clinical and experimental studies in the dog. | Publication Type: | Journal Article | Source of Publication: | Research in Veterinary Science, 40(3), p. 347-351 | Publisher: | Elsevier Ltd | Place of Publication: | United Kingdom | ISSN: | 1532-2661 0034-5288 |
Fields of Research (FoR) 2008: | 060602 Animal Physiology - Cell | Socio-Economic Objective (SEO) 2008: | 920106 Endocrine Organs and Diseases (excl. Diabetes) | Peer Reviewed: | Yes | HERDC Category Description: | C1 Refereed Article in a Scholarly Journal | Publisher/associated links: | http://www.ncbi.nlm.nih.gov/pubmed/3526485 |
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Appears in Collections: | Journal Article School of Science and Technology |
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