Effect of fasting and dexamethasone on binding characteristics of canine erythrocyte insulin receptors

Title
Effect of fasting and dexamethasone on binding characteristics of canine erythrocyte insulin receptors
Publication Date
1986
Author(s)
Dieberg, Gudrun
( author )
OrcID: https://orcid.org/0000-0001-7191-182X
Email: gdieberg@une.edu.au
UNE Id une-id:gdieberg
Sartin, JL
Kemppainen, RJ
Oliver, EH
Type of document
Journal Article
Language
en
Entity Type
Publication
Publisher
Elsevier Ltd
Place of publication
United Kingdom
UNE publication id
une:10795
Abstract
Insulin binding characteristics of canine erythrocyte insulin receptors were studied before and after a 72-hour fast, and one and three days following glucocorticoid (dexamethasone) administration. The 72-hour fast tended to increase maximum insulin binding, but no significant differences were found. The administration of dexamethasone resulted in an increased maximum binding of insulin to its receptors which, at day 1, was due to an increase in receptor concentration, and at day 3, to an increased insulin binding affinity of the receptor. These data suggest that the erythrocyte insulin receptor may be useful in clinical and experimental studies in the dog.
Link
Citation
Research in Veterinary Science, 40(3), p. 347-351
ISSN
1532-2661
0034-5288
Start page
347
End page
351

Files:

NameSizeformatDescriptionLink