Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/10156
Title: Immunological and Antioxidant properties of Astralgaulus complex, Andrographis complex, Cat's claw, Baptisia and Pokeroot
Contributor(s): Glyde, Nicarla (author)orcid ; Agnew, Linda  (author)orcid ; Bone, Kerry (author); Lehmann, Reg (author)
Publication Date: 2011
Handle Link: https://hdl.handle.net/1959.11/10156
Abstract: It has been reported that at least 50% of the Australian population use some form of Complementary and Alternative Medicine (CAM). Furthermore during 2004 consumers spent AU$1.86 billion on CAM which was four times as much as was spent on the Pharmaceutical Benefits Scheme (1). In many countries CAM has traditionally been used to support health in general or to alleviate symptoms or to treat disease. However there is a distinct lack of evidence surrounding the efficacy and mode of action of CAMs and in particular herbal medicines. It has therefore been concluded that there is a need for improved scientific evidence and quality control of herbal preparations with respect to acceptance by the medical community. We have previously reported that Echinacea preparations improved antioxidant and immunological defences (2). In the current project we extended this line of investigation by examining a panel of antioxidant (erythrocyte haemolysis, total phenolic content, Ferric Reducing Ability of Plasma and DPPH radical scavenging assays) and immunological (leukocyte coping capacity, Th1 and Th2 cytokines and leukocyte heat shock protein 70 expression) parameters of a range of practitioner-only herbal products. The products examined were Astralgaulus complex, Andrographis complex, Cat's claw, Baptisia and Pokeroot. We conducted ex vivo studies using peripheral blood samples collected from 10 healthy individuals (5 male and 5 female). The results of this pilot study provide evidence of the antioxidant and immunological properties of these herbal medicines in an ex vivo system and indicate that placebo-controlled, double-blind, clinical trials are warranted.
Publication Type: Conference Publication
Conference Details: ASI 2011: 41st Annual Meeting of the Australasian Society for Immunology, Adelaide, Australia, 11th - 15th December, 2011
Source of Publication: Proceedings of the ASI Annual Scientific Meeting 2011, p. 134-135
Publisher: Australasian Society for Immunology
Place of Publication: Australia
Fields of Research (FoR) 2008: 110704 Cellular Immunology
110399 Clinical Sciences not elsewhere classified
110499 Complementary and Alternative Medicine not elsewhere classified
Socio-Economic Objective (SEO) 2008: 920108 Immune System and Allergy
920412 Preventive Medicine
HERDC Category Description: E3 Extract of Scholarly Conference Publication
Appears in Collections:Conference Publication
School of Science and Technology

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