The importance of population structure on the accuracy of genomic prediction in a multi-breed sheep population

Title
The importance of population structure on the accuracy of genomic prediction in a multi-breed sheep population
Publication Date
2011
Author(s)
Daetwyler, H D
Kemper, K E
Van Der Werf, Julius H
( author )
OrcID: https://orcid.org/0000-0003-2512-1696
Email: jvanderw@une.edu.au
UNE Id une-id:jvanderw
Hayes, B J
Editor
Editor(s): William Pattie
Type of document
Conference Publication
Language
en
Entity Type
Publication
Publisher
Association for the Advancement of Animal Breeding and Genetics (AAABG)
Place of publication
Armidale, Australia
UNE publication id
une:10292
Abstract
Population structure, due to breed, strains and sire family, influences the accuracy of genomic prediction. We investigated principle component analysis as a way to account for population structure in within and across breed genomic prediction of greasy fleece weight and eye muscle depth in multi-breed sheep data. Population structure (including for example half sib family relationships) is responsible for a large proportion of the accuracy of genomic prediction. Correcting for it increased accuracy of greasy fleece weight across breed prediction, but reduced accuracy of across breed prediction for eye muscle depth for breeds not in the reference set. However, the correction reduced within breed accuracy.
Link
Citation
Proceedings of the Association for the Advancement of Animal Breeding and Genetics, v.19, p. 327-330
ISSN
1328-3227
ISBN
9780646559155
Start page
327
End page
330

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