Giallauria, Francesco

Cittadini, Antonio

Smart, Neil

Vigorito, Carlo

2015

Aging is inexorably accompanied by a progressive decline of muscle mass, quality and strength. The resulting condition has been termed sarcopenia. Age-related sarcopenia can be accelerated by a variety of factors including changes in the hormonal milieu, inactivity, poor nutrition, chronic illness, and loss of integrity and function in the peripheral and central nervous systems. The downstream mechanisms by which these risk factors cause sarcopenia are not completely understood. Exercise training (particularly resistance training) has long been identified as the most promising method for increasing muscle mass and strength among older people. New interventions aimed at preventing muscle atrophy, promoting muscle growth and ultimately, maintaining muscle functions during aging are discussed. Understanding how age affects muscle-related gene expression, protein recycling and resynthesis, post-translational modification and turnover will be crucial to identify new treatment options.

Monaldi Archives for Chest Disease: Cardiac Series, 84(1-2), p. 1-3

2465-1028

1122-0643

https://hdl.handle.net/1959.11/19200

en

Pagepress

Resistance training and sarcopenia

Journal Article

Publication