Genome-wide association study of first lambing age and lambing interval in sheep

Author(s)
Abdoli, R
Mirhoseini, S Z
Ghavi Hossein-Zadeh, N
Zamani, P
Moradi, M H
Ferdosi, M H
Gondro, C
Publication Date
2019-09
Abstract
First lambing age and lambing interval are among the most important reproductive traits affecting profitability of sheep breeding systems. Genome-wide association studies (GWAS) were performed on estimated breeding values (EBVs) for age at first lambing and the lambing interval between first and second lambing in Lori-Bakhtiari ewes. Animals were genotyped using the Illumina Ovine SNP50 K genotyping array. Two single nucleotide polymorphisms (SNPs) associated with lambing interval were identified on chromosomes 1 and 2 (Bonferroni adjusted P-value<0.05). No SNP associated with first lambing age was detected. SNP s50067.1 on sheep chromosome 2:86798921 is within a candidate gene; ADAMTS like 1 (ADAMTSL1), known to be involved in proteolysis, peptidase activity, biological process and reproductive pathways in mammalian species. No candidate gene was detected for SNP OAR1_57568179.1 on chromosome 1. The results of the present study may provide new insights into the genomic regions involved in reproductive traits of sheep.
Citation
Small Ruminant Research, v.178, p. 43-45
ISSN
0921-4488
Link
Language
en
Publisher
Elsevier BV
Title
Genome-wide association study of first lambing age and lambing interval in sheep
Type of document
Journal Article
Entity Type
Publication

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