Improving REML estimates of genetic parameters through penalties on correlation matrices

Author(s)
Meyer, Karin
Publication Date
2014
Abstract
Penalized REML estimation can substantially reduce sampling variation in estimates of covariance matrices, and yield estimates of genetic parameters closer to population values than standard analyses. A number of suitable penalties based on prior distributions of correlation matrices from the Bayesian literature are described, and a simulation study is presented demonstrating their efficacy. Results show that reductions of 'loss' in estimates of the genetic covariance matrix, a conglomerate of sampling variance and bias, well over 50% are readily obtained for multivariate analyses of small samples. Default settings for a mild degree of penalization are proposed, which make such analyses suitable for routine use without increasing computational requirements.
Citation
Proceedings of the 10th World Congress on Genetics Applied to Livestock Production (WCGALP) (Methods and Tools: Statistical methods - linear and nonlinear models), p. 1-3
Link
Publisher
American Society of Animal Science
Title
Improving REML estimates of genetic parameters through penalties on correlation matrices
Type of document
Conference Publication
Entity Type
Publication

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