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N-Acyloxy-N-alkoxyamides - structure, properties, reactivity and biological activity |
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10.1016/S0065-3160(07)42002-0 |
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The properties of amides are determinants of the structure and characteristics of a wide range of molecules and particularly those of peptides and proteins. Universally, amides and amide linkages are characterised by a nitrogen that is largely Sp² hybridised and in which the lone pair resides in a 2pz orbital. As a consequence thereis a strong interaction between the amide nitrogen and the carbonyl. |
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Advances in Physical Organic Chemistry, v.42, p. 35-123 |
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