Assessing Anthelmintic Resistance on Small Ruminant Farms in a Tropical Production System

Title
Assessing Anthelmintic Resistance on Small Ruminant Farms in a Tropical Production System
Publication Date
2025-03
Author(s)
Kour, Gurdeep
Alves Correa Carvalho da Silva, Tiago
( author )
OrcID: https://orcid.org/0000-0001-6138-9863
Email: talvesco@une.edu.au
UNE Id une-id:talvesco
Walkden-Brown, Stephen W
( author )
OrcID: https://orcid.org/0000-0002-0638-5533
Email: swalkden@une.edu.au
UNE Id une-id:swalkden
Baleiverata, Alice
Mala, Shayna
Rao, Ritesh
Prasad, Divesh
Cowley, Frances C
( author )
OrcID: https://orcid.org/0000-0002-6475-1503
Email: fcowley@une.edu.au
UNE Id une-id:fcowley
Type of document
Journal Article
Language
en
Entity Type
Publication
Publisher
Elsevier BV
Place of publication
The Netherlands
DOI
10.1016/j.smallrumres.2025.107446
UNE publication id
une:1959.11/64606
Abstract

Imidazothiazoles and benzimidazole are the only classes of anthelmintic drugs that have been used over the past 40 years in Fiji. Recently, concerns have arisen that anthelminthic resistance could be widespread and affect animal health and productivity in Fiji. The present study was designed to evaluate the current anthelmintic resistance status in Fiji’s small ruminant farms. The study included 11 farms from the two (Western and Northern divisions) most relevant areas of small ruminant production in Fiji. The anthelmintic treatments tested were levamisole (LEV), albendazole (ALB), levamisole + albendazole combination (LEV+ALB), ivermectin (IVM), moxidectin (MOX), closantel (CLO) and a negative control (CON). The anthelmintic’s efficacy was tested using faecal egg count reduction (FECR) tests and copro-cultures on days 14, 28, and 42 after treatment administration. The lowest mean FECR on day 14 was observed for ALB (65.2 %) followed by LEV (91.6 %), ALB + LEV (94.3 %), IVM (97.4 %) and MOX (98.8 %). The most relevant genera of GIN encountered were Haemonchus and Tri chostrongylus spp., with no distinct pattern of resistance to drug groups between the two populations. None of the tested drugs (MOX and CLO) presented FECR over 95 % on days 28 and 42. Overall, the level of anthelmintic resistance observed was lower than hypothesised for this study. The combination of LEV+ALB has proven effective and presents an appealing treatment option for managing anthelmintic resistance and worm burden reduction in Fiji.

Link
Citation
Small Ruminant Research, v.244, p. 1-10
ISSN
1879-0941
0921-4488
Start page
1
End page
10
Rights
Attribution 4.0 International

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